ARG45695
anti-PCOLCE / PCPE1 antibody
anti-PCOLCE / PCPE1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PCOLCE / PCPE1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PCOLCE / PCPE1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PCOLCE / PCPE1. |
| Conjugation | Un-conjugated |
| Alternate Names | PCOLCE; Type I procollagen COOH-terminal proteinase enhancer; Procollagen C-endopeptidase enhancer 1; Procollagen C-proteinase enhancer 1; PCPE-1; Type 1 procollagen C-proteinase enhancer protein; PCPE1; Procollagen COOH-terminal proteinase enhancer 1; PCPE |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15113 Human Procollagen C-endopeptidase enhancer 1 |
|---|---|
| Gene Symbol | PCOLCE |
| Gene Full Name | procollagen C-endopeptidase enhancer |
| Background | Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008] |
| Function | Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 48 kDa |
| PTM | C-terminally processed at multiple positions. [UniProt] |
