ARG43915
anti-PDXP antibody
anti-PDXP antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PDXP |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PDXP |
| Antigen Species | Human |
| Immunogen | Human PDXP recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Chronophin |
| Alternate Names | PDXP; Pyridoxal Phosphatase; CIN; Chronophin; DJ37E16.5; Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase; Pyridoxal Phosphate Phosphatase; PLP Phosphatase; EC 3.1.3.74; FLJ32703; PLP; Testicular Secretory Protein Li 36; EC 3.1.3.16; EC 3.1.3; PLPP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PDXP |
| Gene Full Name | Pyridoxal Phosphatase |
| Background | Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP. |
| Function | Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskeleton reorganization, being required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phosphothreonines in LIMK1. Does not dephosphorylate peptides containing phosphotyrosine. |
| Cellular Localization | Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
| Calculated MW | 32 kDa |
Images (4) Click the Picture to Zoom In
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ARG43915 anti-PDXP antibody WB image
Western blot: SH-SY5Y stained with ARG43915 anti-PDXP antibody at 0.5 μg/mL dilution.
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ARG43915 anti-PDXP antibody FACS image
Flow Cytometry: HEL cells stained with ARG43915 anti-PDXP antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43915 anti-PDXP antibody WB image
Western blot: Rat brain stained with ARG43915 anti-PDXP antibody at 0.5 μg/mL dilution.
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ARG43915 anti-PDXP antibody WB image
Western blot: Mouse brain stained with ARG43915 anti-PDXP antibody at 0.5 μg/mL dilution.
