ARG45713
anti-PERM1 antibody
anti-PERM1 antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PERM1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PERM1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PERM1. |
| Conjugation | Un-conjugated |
| Alternate Names | PERM1; PPARGC1 And ESRR Induced Regulator, Muscle 1; C1orf170; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 And Estrogen-Related Receptor-Induced Regulator In Muscle 1; PGC-1 And ERR-Induced Regulator In Muscle Protein 1; PPARGC1 And ESRR-Induced Regulator In Muscle 1; RP11-54O7.8; MGC13275; PGC-1- And ERR-Induced Regulator In Muscle 1; PGC-1 And ERR-Induced Regulator In Muscle 1; Chromosome 1 Open Reading Frame 170 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 75 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5SV97 Human PGC-1 and ERR-induced regulator in muscle protein 1 |
|---|---|
| Gene Symbol | PERM1 |
| Gene Full Name | PPARGC1 And ESRR Induced Regulator, Muscle 1 |
| Background | Involved in response to muscle activity. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Regulates the expression of selective PPARGC1A/B and ESRRA/B/G target genes with roles in glucose and lipid metabolism, energy transfer, contractile function, muscle mitochondrial biogenesis and oxidative capacity. Required for the efficient induction of MT-CO2, MT-CO3, COX4I1, TFB1M, TFB2M, POLRMT and SIRT3 by PPARGC1A. Positively regulates the PPARGC1A/ESRRG-induced expression of CKMT2, TNNI3 and SLC2A4 and negatively regulates the PPARGC1A/ESRRG-induced expression of PDK4. . [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 81 kDa |
