ARG40805
anti-PEX14 antibody
anti-PEX14 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PEX14 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PEX14 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 118-377 of Human PEX14 (NP_004556.1). |
| Conjugation | Un-conjugated |
| Alternate Names | NAPP2; dJ734G22.2; Peroxin-14; Peroxisomal membrane anchor protein PEX14; PTS1 receptor-docking protein; PBD13A; Peroxisomal membrane protein PEX14; Pex14p |
Application Instructions
| Predict Reactivity Note | Mouse | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75381 Human Peroxisomal membrane protein PEX14 Swiss-port # Q9R0A0 Mouse Peroxisomal membrane protein PEX14 |
|---|---|
| Gene Symbol | PEX14 |
| Gene Full Name | peroxisomal biogenesis factor 14 |
| Background | This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008] |
| Function | Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin. [UniProt] |
| Cellular Localization | Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt] |
| Calculated MW | 41 kDa |
Images (1) Click the Picture to Zoom In
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ARG40805 anti-PEX14 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon carcinoma stained with ARG40805 anti-PEX14 antibody at 1:100 dilution.
