ARG45401
anti-PFAS antibody
anti-PFAS antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PFAS |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PFAS |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PFAS. |
| Conjugation | Un-conjugated |
| Alternate Names | PFAS; Phosphoribosylformylglycinamidine Synthase; FGAR Amidotransferase; KIAA0361; FGARAT; GATD8; PURL; Formylglycinamide Ribonucleotide Amidotransferase; Phosphoribosylformylglycineamide Amidotransferase; Formylglycinamide Ribotide Amidotransferase; FGAM Synthase; EC; FGAR-AT; FGAMS; Formylglycinamide Ribotide Synthetase; IKZF1/PFAS Fusion |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 145 kDa |
Properties
| Form | Powder |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O15067 Human Phosphoribosylformylglycinamidine synthase Swiss-port # Q5SUR0 Mouse Phosphoribosylformylglycinamidine synthase |
|---|---|
| Gene Symbol | PFAS |
| Gene Full Name | Phosphoribosylformylglycinamidine Synthase |
| Background | Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008] |
| Function | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 145 kDa |
| PTM | Phosphoprotein. [UniProt] |
