ARG45436
anti-PFKFB1 antibody
anti-PFKFB1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PFKFB1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PFKFB1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PFKFB1. |
| Conjugation | Un-conjugated |
| Alternate Names | PFKFB1; 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 1; PFRX; 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; F6PK; Fructose-6-Phosphate,2-Kinase:Fructose-2,6-Bisphosphatase; 6PF-2-K/Fru-2,6-P2ASE Liver Isozyme; 6PF-2-K/Fru-2,6-P2ase Liver Isozyme; HL2K |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P16118 Human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 |
|---|---|
| Gene Symbol | PFKFB1 |
| Gene Full Name | 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 1 |
| Background | This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] |
| Function | Synthesis and degradation of fructose 2,6-bisphosphate. [UniProt] |
| Calculated MW | 55 kDa |
