ARG45261
anti-PLAGL1 / ZAC antibody
anti-PLAGL1 / ZAC antibody for Flow cytometry,ICC/IF,Western blot and Mouse
Overview
| Product Description | Polyclonal antibody recognizes Plagl1 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Plagl1 |
| Antigen Species | Mouse |
| Immunogen | Recombinant protein containing to mouse Plagl1. |
| Conjugation | Un-conjugated |
| Alternate Names | LOT1; ZAC; Pleiomorphic Adenoma Gene-Like 1; Zinc Finger Protein PLAGL1; Lost On Transformation 1; Tumor Suppressor ZAC; Pleiomorphic Adenoma-Like Protein 1; PLAG-Like 1; LOT-1; ZAC1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 51 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Plagl1 |
|---|---|
| Gene Full Name | PLAG1 Like Zinc Finger 1 |
| Background | This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015] |
| Function | Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 51 kDa |
