ARG45734
anti-POGZ antibody
anti-POGZ antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes POGZ |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | POGZ |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human POGZ. |
| Conjugation | Un-conjugated |
| Alternate Names | POGZ; Pogo Transposable Element Derived With ZNF Domain; ZNF280E; ZNF635; Pogo Transposable Element With ZNF Domain; Zinc Finger Protein 280E; KIAA0461; Putative Protein Product Of Nbla00003; Zinc Finger Protein 635; Suppressor Of Hairy Wing Homolog 5; ZNF635m; MRD37; WHSUS; SUHW5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 220 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7Z3K3 Human Pogo transposable element with ZNF domain |
|---|---|
| Gene Symbol | POGZ |
| Gene Full Name | Pogo Transposable Element Derived With ZNF Domain |
| Background | The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010] |
| Function | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. [UniProt] |
| Cellular Localization | Chromosome; Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 155 kDa |
| PTM | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
