ARG44894
anti-POU3F1 / OCT6 antibody
anti-POU3F1 / OCT6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Mouse Monoclonal antibody recognizes POU3F1 / OCT6 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | POU3F1 / OCT6 |
| Antigen Species | Mouse |
| Conjugation | Un-conjugated |
| Alternate Names | POU3F1; POU Class 3 Homeobox 1; OCT6; SCIP; OTF6; POU Domain, Class 3, Transcription Factor 1; Octamer-Binding Transcription Factor 6; POU Domain Transcription Factor SCIP; Octamer-Binding Protein 6; OTF-6; POU Domain Class 3, Transcription Factor 1; Oct-6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purified. |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P20267 Rat POU domain, class 3, transcription factor 1 Swiss-port # P21952 Mouse POU domain, class 3, transcription factor 1 |
|---|---|
| Gene Symbol | POU3F1 |
| Gene Full Name | POU Class 3 Homeobox 1 |
| Background | Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of gene expression; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within keratinocyte differentiation; nervous system development; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes. [Uniprot] |
| Cellular Localization | Nucleus. [Uniprot] |
| Calculated MW | 45 kDa |
Images (2) Click the Picture to Zoom In
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ARG44894 anti-POU3F1 / OCT6 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44894 anti-POU3F1 / OCT6 antibody at 5 µg/mL dilution.
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ARG44894 anti-POU3F1 / OCT6 antibody WB image
Western blot: Rat brain stained with ARG44894 anti-POU3F1 / OCT6 antibody at 1 µg/mL dilution.
