ARG45535

anti-PPP2R3A antibody

anti-PPP2R3A antibody for Flow cytometry,ICC/IF,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes PPP2R3A
Tested Reactivity Hu
Tested Application FACS, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PPP2R3A
Antigen Species Human
Immunogen Recombinant protein containing to human PPP2R3A.
Conjugation Un-conjugated
Alternate Names PPP2R3A; Protein Phosphatase 2 Regulatory Subunit B''Alpha; PPP2R3; PR130; PR72; Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit B'' Subunit Alpha; Serine/Threonine-Protein Phosphatase 2A 72/130 KDa Regulatory Subunit B; PR130/B''Alpha1 Subunit; PR72/B''Alpha2 Subuit; Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit B'' (PR 72), Alpha Isoform And (PR 130), Beta Isoform; Protein Phosphatase 2, Regulatory Subunit B'', Alpha; PP2A Subunit B Isoforms B''-PR72/PR130; PP2A Subunit B Isoform PR72/PR130; PP2A Subunit B Isoform R3 Isoform; PP2A Subunit B Isoforms B72/B130

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
WB0.1-0.25 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 128 kDa

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5523 Human PPP2R3A

Swiss-port # Q06190 Human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alp

Gene Symbol PPP2R3A
Gene Full Name Protein Phosphatase 2 Regulatory Subunit B''Alpha
Background This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. [UniProt]
Calculated MW 130 kDa