ARG45931
anti-Pericentrin 1 / FROUNT antibody
anti-Pericentrin 1 / FROUNT antibody for Western blot,ICC/IF,Flow cytometry and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Pericentrin 1 / FROUNT |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Pericentrin 1 / FROUNT |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Pericentrin 1 / FROUNT. |
| Conjugation | Un-conjugated |
| Alternate Names | Nucleoporin 85; NUP85; NUP75; PCNT1; Nuclear pore complex protein Nup85; 85 kDa nucleoporin; FROUNT; Nucleoporin Nup75; Nucleoporin Nup85; Pericentrin-1 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 60 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NUP85 |
| Gene Full Name | Nucleoporin 85 |
| Background | This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Function | Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance [UniProt] |
| Cellular Localization | Centromere; Chromosome; Cytoplasm; Cytoskeleton; Kinetochore; Membrane; Nuclear pore complex; Nucleus. [UniProt] |
| Calculated MW | 75 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
