ARG45953
anti-Phosphoribosyl pyrophosphate amidotransferase antibody
anti-Phosphoribosyl pyrophosphate amidotransferase antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Phosphoribosyl pyrophosphate amidotransferase |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Phosphoribosyl pyrophosphate amidotransferase |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Phosphoribosyl pyrophosphate amidotransferase. |
| Conjugation | Un-conjugated |
| Alternate Names | Phosphoribosyl Pyrophosphate Amidotransferase; PPAT; GPAT; Amidophosphoribosyltransferase; ATase; EC 2.4.2.14; Glutamine phosphoribosylpyrophosphate amidotransferase; GPAT |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 57 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PPAT |
| Gene Full Name | Phosphoribosyl Pyrophosphate Amidotransferase |
| Background | The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. [UniProt] |
| Cellular Localization | Cytosol. [UniProt] |
| Calculated MW | 57 kDa |
| PTM | Acetylation. [UniProt]. [UniProt] |
