ARG62963
anti-Proinsulin (C-peptide) antibody [C-PEP-01] (Biotin)
anti-Proinsulin (C-peptide) antibody [C-PEP-01] (Biotin) for IHC-Formalin-fixed paraffin-embedded sections and Human
Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Biotin-conjugated Mouse Monoclonal antibody [C-PEP-01] recognizes Proinsulin (C-peptide) |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Specificity | The clone C-PEP-01 reacts specifically with C-peptide, a part of the Proinsulin molecule. Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule). No cross-reactivity with Insulin or other peptide hormones or proteins was observed. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C-PEP-01 |
| Isotype | IgG1 |
| Target Name | Proinsulin (C-peptide) |
| Antigen Species | Human |
| Immunogen | Human C-peptide conjugated to bovine serum albumin. |
| Conjugation | Biotin |
| Alternate Names | IDDM; IDDM2; IDDM1; ILPR; MODY10; Insulin; IRDN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification Note | The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin. |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | INS |
| Gene Full Name | insulin |
| Background | From every molecule of Proinsulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin. |
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 12 kDa |
Clone References
A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA.
