ARG45635
anti-RAPH1 antibody
anti-RAPH1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RAPH1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RAPH1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human RAPH1. |
| Conjugation | Un-conjugated |
| Alternate Names | RAPH1; Ras Association (RalGDS/AF-6) And Pleckstrin Homology Domains 1; KIAA1681; ALS2CR18; ALS2CR9; Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 18; Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 9; Ras-Associated And Pleckstrin Homology Domains-Containing Protein 1; Proline-Rich EVH1 Ligand 2; Lamellipodin; PREL-2; PREL2; RMO1; LPD; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 18 Protein; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 9 Protein; Protein RMO1; RalGDS/AF-6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q70E73 Human Ras-associated and pleckstrin homology domains-containing protein 1 |
|---|---|
| Gene Symbol | RAPH1 |
| Gene Full Name | Ras Association (RalGDS/AF-6) And Pleckstrin Homology Domains 1 |
| Background | This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] |
| Function | Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion. [UniProt] |
| Cellular Localization | Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Membrane. [UniProt] |
| Calculated MW | 135 kDa |
| PTM | Acetylation; Phosphoprotein |
