ARG59108
anti-RNASE1 / Ribonuclease A antibody
anti-RNASE1 / Ribonuclease A antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RNASE1 / Ribonuclease A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RNASE1 / Ribonuclease A |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 72-90 of Human RNASE1 / Ribonuclease A. (NTFVHEPLVDVQNVCFQEK) |
| Conjugation | Un-conjugated |
| Alternate Names | Ribonuclease A; RNase A; RNS1; RAC1; RIB1; EC 3.1.27.5; Ribonuclease 1; RNase 1; Ribonuclease pancreatic; RNase UpI-1; RIB-1; HP-RNase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RNASE1 |
| Gene Full Name | ribonuclease, RNase A family, 1 (pancreatic) |
| Background | This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| Function | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 18 kDa |
| PTM | N-linked glycans are of complex type. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG59108 anti-RNASE1 / Ribonuclease A antibody WB image
Western blot: 40 µg of MCF-7, U87, HeLa, MDA-MB-231, Jurkat, SMMC-7721, COLO320, SW620 and CEM cell lysates stained with ARG59108 anti-RNASE1 / Ribonuclease A antibody at 0.5 µg/ml dilution.
