ARG44921
anti-RNF207 antibody
anti-RNF207 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes RNF207 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | RNF207 |
| Antigen Species | Human |
| Epitope | SLQLDVQIAS EHASLEGMRV VFQEIWEEAY QRVANEQEIY EAQLHDLLQL RQENAYLTTI TKQITPYVRS IAKVKERLEP RFQAPVDEQS ESLQNTHDDS RNNAASARNN PGSVPEKREK TSEPKGNSWA PNGLSEEPLL |
| Conjugation | Un-conjugated |
| Alternate Names | RNF207; Ring Finger Protein 207; C1orf188; FLJ46380; FLJ32096; Chromosome 1 Open Reading Frame 188; RING Finger Protein 207; OTTHUMG00000001089 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RNF207 |
| Gene Full Name | Ring Finger Protein 207 |
| Background | Enables Hsp70 protein binding activity; chaperone binding activity; and transmembrane transporter binding activity. Involved in positive regulation of delayed rectifier potassium channel activity; positive regulation of gene expression; and positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 71 kDa |
Images (1) Click the Picture to Zoom In
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ARG44921 anti-RNF207 antibody IHC-P image
Immunohistochemistry: Human heart muscle stained with ARG44921 anti-RNF207 antibody at 5 µg/mL dilution.
