ARG44885
anti-RNF219 antibody
anti-RNF219 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes RNF219 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | RNF219 |
| Antigen Species | Human |
| Epitope | DKHLVTDNPS KINPETVAEW KKKLRTANEI YEKVKDDVDK LKEANKKLKL ENGGLVRENL RLKAEVDNRS PQKFGRFAVA ALQSKVEQYE RETNRLKKAL ERSDKYIEEL ESQVAQLKNS SEEKEAMNSI CQTALSADGK GSKGSEEDVV |
| Conjugation | Un-conjugated |
| Alternate Names | OBI1; ORC Ubiquitin Ligase 1; C13orf7; RNF219; Ring Finger Protein 219; FLJ13449; Chromosome 13 Open Reading Frame 7; RING Finger Protein 219; EC 2.3.2.27 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | OBI1 |
| Gene Full Name | ORC Ubiquitin Ligase 1 |
| Background | Enables chromatin binding activity and ubiquitin-protein transferase activity. Involved in protein autoubiquitination; protein monoubiquitination; and regulation of DNA replication. Located in chromatin. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase. [Uniprot] |
| Cellular Localization | Chromosome. [Uniprot] |
| PTM | Phosphoprotein, Ubl conjugation. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG44885 anti-RNF219 antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44885 anti-RNF219 antibody at 5 µg/mL dilution.
