ARG45306
anti-RNase H1 / RNH1 antibody
anti-RNase H1 / RNH1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Polyclonal antibody recognizes RNase H1 / RNH1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RNase H1 / RNH1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human RNase H1 / RNH1. |
| Conjugation | Un-conjugated |
| Alternate Names | RNASEH1; Ribonuclease H1; Ribonuclease H Type II; RNase H1; RNH1; EC 3.1.26.4; H1RNA; PEOB2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 38 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RNASEH1 |
| Gene Full Name | Ribonuclease H1 |
| Background | This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017] |
| Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 32 kDa |
