ARG45131
anti-SAP102 antibody
anti-SAP102 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SAP102 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SAP102 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SAP102. |
| Conjugation | Un-conjugated |
| Alternate Names | DLG3 ; Disks large homolog 3; DLG3; MRX; SAP102; NEDLG; SAP-102; Neuroendocrine-DLG; Synapse-associated protein 102; MRX90; Disks large homolog 3; PPP1R82; XLMR |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 102 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DLG3 |
| Gene Full Name | Disks large homolog 3 |
| Background | This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
| Function | Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. [UniProt] |
| Cellular Localization | adherens junction; AMPA glutamate receptor complex; basolateral plasma membrane; bicellular tight junction; cytosol; extracellular space; glutamatergic synapse neuromuscular junction; neuron projection; plasma membrane; postsynaptic density membrane. [UniProt] |
| Calculated MW | 90 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
