ARG45267
anti-SF3A3 antibody
anti-SF3A3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes SF3A3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SF3A3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SF3A3. |
| Conjugation | Un-conjugated |
| Alternate Names | SF3A3; Splicing Factor 3a Subunit 3; SF3a60; SAP61; PRPF9; PRP9; Splicing Factor 3a, Subunit 3, 60kDa; Splicing Factor 3a, Subunit 3, 60kD; SAP 61; Pre-MRNA Splicing Factor SF3a (60kD); Spliceosome Associated Protein 61; Spliceosome-Associated Protein 61; Splicing Factor 3A Subunit 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 59 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SF3A3 |
| Gene Full Name | Splicing Factor 3a Subunit 3 |
| Background | This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| Function | Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. [UniProt] |
| Cellular Localization | Nucleus; Spliceosome. [UniProt] |
| Calculated MW | 59 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
