ARG45402
anti-SLC25A13/Citrin antibody
anti-SLC25A13/Citrin antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC25A13/Citrin |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC25A13/Citrin |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SLC25A13/Citrin. |
| Conjugation | Un-conjugated |
| Alternate Names | SLC25A13; Solute Carrier Family 25 Member 13; ARALAR2; Calcium-Binding Mitochondrial Carrier Protein Aralar2; Mitochondrial Aspartate Glutamate Carrier 2; CITRIN; Electrogenic Aspartate/Glutamate Antiporter SLC25A13, Mitochondrial; Solute Carrier Family 25 (Aspartate/Glutamate Carrier), Member 13; Citrullinemia Type II; ARALAR-Related Gene; CTLN2; Solute Carrier Family 25, Member 13 (Citrin); Citrin; NICCD |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 70 kDa |
Properties
| Form | Powder |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9UJS0 Human Calcium-binding mitochondrial carrier protein Aralar2 |
|---|---|
| Gene Symbol | SLC25A13 |
| Gene Full Name | Solute Carrier Family 25 Member 13 |
| Background | This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. [UniProt] |
| Cellular Localization | Membrane; Mitochondrion; Mitochondrion inner membrane. [UniProt] |
| Calculated MW | 74 kDa |
| PTM | Acetylation; Methylation; Phosphoprotein. [UniProt] |
