ARG42068
anti-SLC6A8 antibody
anti-SLC6A8 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC6A8 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Gpig, Hrs, Rb |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC6A8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the N-terminal region of Human SLC6A8. (within the following region: CDQLA DRRSP VIEFW ENKVL RLSGG LEVPG ALNWE VTLCL LACWV LVYFC) |
| Conjugation | Un-conjugated |
| Alternate Names | Solute carrier family 6 member 8; CCDS1; CT1; CRT; Creatine transporter 1; CRTR; CTR5; Sodium- and chloride-dependent creatine transporter 1 |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100% | ||||
|---|---|---|---|---|---|
| Application Suggestion |
|
||||
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P48029 Human Sodium- and chloride-dependent creatine transporter 1 |
|---|---|
| Gene Symbol | SLC6A8 |
| Gene Full Name | solute carrier family 6 (neurotransmitter transporter), member 8 |
| Background | The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| Function | Required for the uptake of creatine in muscles and brain. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 71 kDa |
Images (1) Click the Picture to Zoom In
-
ARG42068 anti-SLC6A8 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human skeletal muscle tissue stained with ARG42068 anti-SLC6A8 antibody at 4 - 8 µg/ml dilution.
