ARG44587
anti-SOX2 antibody
anti-SOX2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Monoclonal antibody recognizes SOX2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Target Name | SOX2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to internal region of human SOX2. |
| Conjugation | Un-conjugated |
| Alternate Names | SOX2; SRY-Box Transcription Factor 2; SRY (Sex Determining Region Y)-Box 2; Transcription Factor SOX-2; SRY-Box 2; Sex Determining Region Y-Box 2; SRY-Related HMG-Box Gene 2; Transcription Factor SOX2; MCOPS3; ANOP3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity Purified |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SOX2 |
| Gene Full Name | SRY-Box Transcription Factor 2 |
| Background | This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008] |
| Function | Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. [UniProt] |
| Cellular Localization | Cytoplasm, Nucleus. [UniProt] |
| Calculated MW | 34 kDa |
Images (3) Click the Picture to Zoom In
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ARG44587 anti-SOX2 antibody IHC-P image
Immunohistochemistry: Human cervix carcinoma stained with ARG44587 anti-SOX2 antibody.
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ARG44587 anti-SOX2 antibody ICC/IF image
Immunofluorescence: NCCIT stained with ARG44587 anti-SOX2 antibody.
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ARG44587 anti-SOX2 antibody WB image
Western blot: F9 stained with ARG44587 anti-SOX2 antibody.
