ARG45285
anti-SPRED2 antibody
anti-SPRED2 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes SPRED2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SPRED2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SPRED2. |
| Conjugation | Un-conjugated |
| Alternate Names | SPRED2; Sprouty Related EVH1 Domain Containing 2; Spred-2; Sprouty-Related, EVH1 Domain-Containing Protein 2; FLJ21897; FLJ31917; Sprouty Protein With EVH-1 Domain 2, Related Sequence; NS14 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 53 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SPRED2 |
| Gene Full Name | Sprouty Related EVH1 Domain Containing 2 |
| Background | SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008] |
| Function | Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. [UniProt] |
| Cellular Localization | Cell membrane; Cytoplasm; Cytoplasmic vesicle; Membrane. [UniProt] |
| Calculated MW | 48 kDa |
| PTM | Phosphoprotein; Ubl conjugation. [UniProt] |
