ARG45655
anti-SSX2IP antibody
anti-SSX2IP antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SSX2IP |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SSX2IP |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SSX2IP. |
| Conjugation | Un-conjugated |
| Alternate Names | SSX2IP; SSX Family Member 2 Interacting Protein; HMsd1; Synovial Sarcoma, X Breakpoint 2 Interacting Protein; Afadin- And Alpha-Actinin-Binding Protein; Afadin DIL Domain-Interacting Protein; SSX2-Interacting Protein; ADIP; KIAA0923 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 71 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8CGZ2 Rat Afadin- and alpha-actinin-binding protein Swiss-port # Q9Y2D8 Human Afadin- and alpha-actinin-binding protein |
|---|---|
| Gene Symbol | SSX2IP |
| Gene Full Name | SSX Family Member 2 Interacting Protein |
| Background | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] |
| Function | Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. [UniProt] |
| Cellular Localization | Cell junction; Cell projection; Cytoplasm; Cytoskeleton; Nucleus. [UniProt] |
| Calculated MW | 71 kDa |
| PTM | Phosphoprotein. [UniProt] |
