ARG45288

anti-SUCLG2 antibody

anti-SUCLG2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Polyclonal antibody recognizes SUCLG2
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SUCLG2
Antigen Species Human
Immunogen Recombinant protein containing to human SUCLG2.
Conjugation Un-conjugated
Alternate Names SUCLG2; Succinate-CoA Ligase GDP-Forming Subunit Beta; Succinate--CoA Ligase [GDP-Forming] Subunit Beta, Mitochondrial; GTP-Specific Succinyl-CoA Synthetase Subunit Beta; EC 6.2.1.4 47; SCS-BetaG; GTPSCS; G-SCS; Succinyl-CoA Ligase [GDP-Forming] Subunit Beta, Mitochondrial; Succinyl-CoA Ligase, GDP-Forming, Beta Chain, Mitochondrial; GTP-Specific Succinyl-CoA Synthetase Beta Subunit; Succinate-CoA Ligase GDP-Forming Beta Subunit; Succinyl-CoA Synthetase, Beta-G Chain; Succinyl-CoA Synthetase Beta-G Chain; EC 6.2.1 47; GBETA

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 47 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20917 Mouse SUCLG2

GeneID: 8801 Human SUCLG2

Swiss-port # Q96I99 Human Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial

Swiss-port # Q9Z2I8 Mouse Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial

Gene Symbol SUCLG2
Gene Full Name Succinate-CoA Ligase GDP-Forming Subunit Beta
Background This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12. [provided by RefSeq, Apr 2010]
Function GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.. [UniProt]
Cellular Localization Mitochondrion. [UniProt]
Calculated MW 47 kDa
PTM Acetylation; Phosphoprotein. [UniProt]