ARG45288
anti-SUCLG2 antibody
anti-SUCLG2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
Product Description | Polyclonal antibody recognizes SUCLG2 |
---|---|
Tested Reactivity | Hu, Ms, Rat |
Tested Application | FACS, ICC/IF, IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | SUCLG2 |
Antigen Species | Human |
Immunogen | Recombinant protein containing to human SUCLG2. |
Conjugation | Un-conjugated |
Alternate Names | SUCLG2; Succinate-CoA Ligase GDP-Forming Subunit Beta; Succinate--CoA Ligase [GDP-Forming] Subunit Beta, Mitochondrial; GTP-Specific Succinyl-CoA Synthetase Subunit Beta; EC 6.2.1.4 47; SCS-BetaG; GTPSCS; G-SCS; Succinyl-CoA Ligase [GDP-Forming] Subunit Beta, Mitochondrial; Succinyl-CoA Ligase, GDP-Forming, Beta Chain, Mitochondrial; GTP-Specific Succinyl-CoA Synthetase Beta Subunit; Succinate-CoA Ligase GDP-Forming Beta Subunit; Succinyl-CoA Synthetase, Beta-G Chain; Succinyl-CoA Synthetase Beta-G Chain; EC 6.2.1 47; GBETA |
Application Instructions
Application Suggestion |
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
Observed Size | 47 kDa |
Properties
Form | Liquid |
---|---|
Purification | Affinity purification with immunogen. |
Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
Stabilizer | 4% Trehalose |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q96I99 Human Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial Swiss-port # Q9Z2I8 Mouse Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial |
---|---|
Gene Symbol | SUCLG2 |
Gene Full Name | Succinate-CoA Ligase GDP-Forming Subunit Beta |
Background | This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12. [provided by RefSeq, Apr 2010] |
Function | GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.. [UniProt] |
Cellular Localization | Mitochondrion. [UniProt] |
Calculated MW | 47 kDa |
PTM | Acetylation; Phosphoprotein. [UniProt] |