ARG54576
anti-Secretogranin II antibody
anti-Secretogranin II antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Rat
Neuroscience antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Secretogranin II |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | IHC-P, IP, WB |
| Specificity | This antibody reacts speci cally with rat and human secretogranin II. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Secretogranin II |
| Antigen Species | Human |
| Immunogen | N-terminal sequence (amino acids 1-19) of rat/human secretogranin II coupled to ovalbumin. |
| Conjugation | Un-conjugated |
| Alternate Names | EM66; Secretogranin II; CHGC; SgII; SN; Secretogranin-2; Chromogranin-C |
Application Instructions
| Application Note | This antibody has been used successfully in Western blot assays (1:2,500 - 1:10,000 dilution) and immuno precipitation of secretogranin II (1:100 - 1:500 dilution), as well as in immunohistochemical identi cation of secretogranin II (1:1,000 dilution). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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Properties
| Form | Liquid |
|---|---|
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SCG2 |
| Gene Full Name | secretogranin II |
| Background | The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008] |
| Function | Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. [UniProt] |
| Research Area | Neuroscience antibody |
| Calculated MW | 71 kDa |
| PTM | O-glycosylated. |
