ARG43849
anti-Semaphorin 4D antibody [133-1C6] (FITC)
anti-Semaphorin 4D antibody [133-1C6] (FITC) for Flow cytometry and Human
Overview
| Product Description | FITC-conjugated Mouse Monoclonal antibody recognizes Semaphorin 4D. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 133-1C6 |
| Isotype | IgM |
| Target Name | Semaphorin 4D |
| Antigen Species | Human |
| Immunogen | PHA stimulated human PBL |
| Conjugation | FITC |
| Protein Full Name | Semaphorin-4D |
| Alternate Names | SEMA4D; Semaphorin 4D; CD100; C9orf164; Coll-4; SEMAJ; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, (Semaphorin) 4D; Semaphorin-4D; FLJ39737; BB18; GR3; A8; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, 4D; Chromosome 9 Open Reading Frame 164; CD100 Antigen; M-Sema G; M-Sema-G; COLL4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein-A affinity chromatography |
| Buffer | PBS (pH 8.0) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 4°C. Keep protected from prolonged exposure to light. Do not freeze. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SEMA4D |
| Gene Full Name | Semaphorin 4D |
| Background | Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of neuron projection development; and regulation of phosphate metabolic process. Is integral component of plasma membrane. |
| Function | Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. |
| Cellular Localization | Cell membrane |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein |
Images (1) Click the Picture to Zoom In
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ARG43849 anti-Semaphorin 4D antibody [133-1C6] (FITC) FACS image
Flow Cytometry: Human whole blood stained with ARG43849 anti-Semaphorin 4D antibody [133-1C6] (FITC) at 5 μg/ml.
