ARG45216
anti-SnoN / SNO antibody
anti-SnoN / SNO antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SnoN / SNO |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SnoN / SNO |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SnoN/SNO/SKIL. |
| Conjugation | Un-conjugated |
| Alternate Names | SKIL; SKI Like Proto-Oncogene; SNO; SnoN; SnoA; SKI-Like Oncogene; Ski-Like Protein; Ski-Related Oncogene SnoN; Ski-Related Oncogene; Ski-Related Protein; SnoI |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 77 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SKIL |
| Gene Full Name | SKI Like Proto-Oncogen |
| Background | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Function | May have regulatory role in cell division or differentiation in response to extracellular signals.. [UniProt] |
| Cellular Localization | acrosomal vesicle; cytoplasm; nucleoplasm; PML body . [UniProt] Nucleus . [UniProt] |
| Calculated MW | 76 kDa |
| PTM | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
