ARG44942
anti-Spindly / CCDC99 antibody
anti-Spindly / CCDC99 antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes Spindly / CCDC99 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | Spindly / CCDC99 |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | SPDL1; Spindle Apparatus Coiled-Coil Protein 1; HSpindly; CCDC99; Coiled-Coil Domain-Containing Protein 99; Rhabdomyosarcoma Antigen MU-RMS-40.4A; Arsenite-Related Gene 1 Protein; Protein Spindly; FLJ20364; Spindle Apparatus Coiled-Coil Domain-Containing Protein 1; Rrhabdomyosarcoma Antigen Protein MU-RMS-40.4A; Coiled-Coil Domain Containing 99; Spindly Homolog (Drosophila) |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SPDL1 |
| Gene Full Name | Spindle Apparatus Coiled-Coil Protein 1 |
| Background | This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins, and in mitotic checkpoint signaling. [provided by RefSeq, Jul 2016] |
| Function | Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). [UniProt] |
| Cellular Localization | Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore, Nucleus. [UniProt] |
| PTM | Acetylation, Phosphoprotein, Ubl conjugation. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG44942 anti-Spindly / CCDC99 antibody WB image
Western blot: HeLa stained with ARG44942 anti-Spindly / CCDC99 antibody at 1 µg/mL dilution.
