ARG45180

anti-Synaptopodin antibody

anti-Synaptopodin antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Synaptopodin
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Synaptopodin
Antigen Species Human
Immunogen Synthetic peptide corresponding to C-terminal region of human Synaptopodin.
Conjugation Un-conjugated
Alternate Names  SYNPO; Synaptopodin; KIAA1029; SYNPO1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
IHC-P2-5 μg/ml
WB0.1-0.25 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 99 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose.
Preservative 0.01% Sodium azide
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11346 Human SYNPO

GeneID: 60324 Rat SYNPO

Swiss-port # Q8N3V7 Human Synaptopodin

Swiss-port # Q9Z327 Rat Synaptopodin

Gene Symbol  SYNPO
Gene Full Name Synaptopodin
Background Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]
Function Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity. [UniProt]
Cellular Localization Cytoplasm, cytoskeleton; Cell junction, tight junction; Perikaryon; Cell projection, dendritic spine; Postsynaptic density; Synapse; Cytoplasm, cytosol. [UniProt]
Calculated MW 99 kDa
PTM Acetylation; Glycoprotein; Phosphoprotein. [UniProt]