ARG42548

anti-TBX18 antibody

anti-TBX18 antibody for Western blot and Human,Mouse,Rat,Dog,Monkey

Overview

Product Description Goat Polyclonal antibody recognizes TBX18
Tested Reactivity Hu, Ms, Rat, Dog, Mk
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name TBX18
Antigen Species Human
Immunogen Recombinant peptide within aa. 330 to the C-terminus of Human TBX18.
Conjugation Un-conjugated
Alternate Names T-box protein 18; T-box transcription factor TBX18

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control H69
Observed Size ~ 68 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.05% Sodium azide and 20% Glycerol.
Preservative 0.05% Sodium azide
Stabilizer 20% Glycerol
Concentration 3 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 76365 Mouse TBX18

GeneID: 9096 Human TBX18

Swiss-port # O95935 Human T-box transcription factor TBX18

Swiss-port # Q9EPZ6 Mouse T-box transcription factor TBX18

Gene Symbol TBX18
Gene Full Name T-box 18
Background This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]
Function Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 65 kDa

Images (1) Click the Picture to Zoom In

  • ARG42548 anti-TBX18 antibody WB image

    Western blot: 50 µg of H69 cell lysate stained with ARG42548 anti-TBX18 antibody at 1:1000 dilution.