ARG44603
anti-TCR Cbeta1 antibody [JOVI.1] (PE-Cyanine 5.5)
anti-TCR Cbeta1 antibody [JOVI.1] (PE-Cyanine 5.5) for Flow cytometry and Human
Overview
| Product Description | PE-Cyanine 5.5-conjugated Mouse Monoclonal antibody recognizes TCR Cbeta1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | JOVI.1 |
| Isotype | IgG2a kappa |
| Target Name | TCR Cbeta1 |
| Antigen Species | Human |
| Immunogen | thymus, spleen, and mesenteric lymph nodes isolated from a mouse transgenic for human TCR Vbeta3Cbeta1 |
| Conjugation | PE-Cyanine 5.5 |
| Alternate Names | TRBC1; T Cell Receptor Beta Constant 1; BV05S1J2.2; TCRBC1; V_segment Translation Product; TCRB |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified antibody is conjugated with activated tandem dye of activated Peridinin-Chlorophyll Protein-Cyanine 5.5 (PerCP-Cy™5.5), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TRBC1 |
| Gene Full Name | T Cell Receptor Beta Constant 1 |
| Background | Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be located in plasma membrane. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity. [UniProt] |
| Cellular Localization | Cell membrane, Membrane, T cell receptor. [UniProt] |
| Calculated MW | 20 kDa |
| PTM | Disulfide bond, Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG44603 anti-TCR Cbeta1 antibody [JOVI.1] (PE-Cyanine 5.5) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG44603 anti-TCR Cbeta1 antibody [JOVI.1] (PE-Cyanine 5.5) at 10 μl/ 100 μl dilution.
