ARG54663
anti-TCTN3 antibody
anti-TCTN3 antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody; Cell Death antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TCTN3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TCTN3 |
| Immunogen | Synthetic peptide (17 aa) within aa. 540-590 of Human TCTN3. |
| Conjugation | Un-conjugated |
| Alternate Names | Tectonic-3; TECT3; C10orf61; JBTS18; OFD4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Positive Control | SK-N-SH Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TCTN3 |
| Gene Full Name | tectonic family member 3 |
| Background | TCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube. | |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody |
| Calculated MW | 66 kDa |
Images (3) Click the Picture to Zoom In
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ARG54663 anti-TCTN3 antibody ICC/IF image
Immunocytochemistry: HeLa cells stained with ARG54663 anti-TCTN3 antibody at 4 μg/ml.
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ARG54663 anti-TCTN3 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG54663 anti-TCTN3 antibody at 20 μg/ml.
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ARG54663 anti-TCTN3 antibody WB image
Western blot: HeLa cell lysate stained with ARG54663 anti-TCTN3 antibody at (A) 1 and (B) 2μg/ml.
