ARG22492
anti-TGN46 antibody
anti-TGN46 antibody for ICC/IF,Western blot and Human,Primates
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TGN46 This antibody recognizes Trans-Golgi network integral membrane protein 2, also known as TGN46, TGN38 homolog or Trans-Golgi network protein TGN51. TGN46 is a 480 amino acid ~110kDa single pass type I transmembrane glycoprotein associated with the trans golgi network membrane. TGN46 has been reported as being the best available marker for human trans-Golgi network. |
|---|---|
| Tested Reactivity | Hu, NHuPrm |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TGN46 |
| Antigen Species | Human |
| Immunogen | Recombinant human TGN46. |
| Conjugation | Un-conjugated |
| Alternate Names | Trans-Golgi network protein TGN51; TGN48; TGN46; TGN51; Trans-Golgi network integral membrane protein 2; TGN38 homolog; TTGN2; TGN38 |
Application Instructions
| Application Suggestion |
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| Application Note | ICC/IF: Fixation of tissues with 3% paraformaldehyde or methanol is recommended prior to using this antibody on immunofluorescence. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | Serum, 0.02% Sodium azide, 50% Glycerol and 1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O43493 Human Trans-Golgi network integral membrane protein 2 |
|---|---|
| Gene Symbol | TGOLN2 |
| Gene Full Name | trans-golgi network protein 2 |
| Background | This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| Function | May be involved in regulating membrane traffic to and from trans-Golgi network. [UniProt] |
| Calculated MW | 46 kDa (unmodified). 110-120 kDa (glycosylated) |
