Overview

Product Description	Rabbit Polyclonal antibody recognizes TGN46
Tested Reactivity	Hu
Tested Application	IHC-P, IP, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	TGN46
Antigen Species	Human
Immunogen	Synthetic peptide of Human TGN46.
Conjugation	Un-conjugated
Alternate Names	Trans-Golgi network protein TGN51; TGN48; TGN46; TGN51; Trans-Golgi network integral membrane protein 2; TGN38 homolog; TTGN2; TGN38

Application Instructions

Application Suggestion	Tested Application Dilution IHC-P 1:50 - 1:200 IP 1:50 WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	HeLa

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 10618 Human TGOLN2 Swiss-port # O43493 Human Trans-Golgi network integral membrane protein 2
Gene Symbol	TGOLN2
Gene Full Name	trans-golgi network protein 2
Background	This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Function	May be involved in regulating membrane traffic to and from trans-Golgi network. [UniProt]
Cellular Localization	Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes. [UniProt]
Calculated MW	46 kDa

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