ARG44752
anti-THOP1 / Thimet Oligopeptidase antibody
anti-THOP1 / Thimet Oligopeptidase antibody for Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes THOP1 / Thimet Oligopeptidase |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | THOP1 / Thimet Oligopeptidase |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | EP24.15; TOP; Thimet oligopeptidase; MEPD_HUMAN; EC 3.4.24.15; Endopeptidase 24.15; MP78 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | THOP1 |
| Gene Full Name | thimet oligopeptidase 1 |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 79 kDa |
Images (1) Click the Picture to Zoom In
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ARG44752 anti-THOP1 / Thimet Oligopeptidase antibody IP image
Immunoprecipitation: K562 lysate immunoprecipitated with 2.5 µg of ARG44752 anti-THOP1 / Thimet Oligopeptidase antibody.
