ARG44017
anti-TIM1 / KIM1 antibody
anti-TIM1 / KIM1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TIM1 / KIM1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TIM1 / KIM1 |
| Antigen Species | Human |
| Immunogen | Human TIM1 / KIM1 recombinantprotein |
| Conjugation | Un-conjugated |
| Protein Full Name | Hepatitis A virus cellular receptor 1 |
| Alternate Names | HAVCR1; Hepatitis A Virus Cellular Receptor 1; TIM-1; TIMD1; TIM1; KIM1; Kidney Injury Molecule 1; HAVCR-1; HAVCR; CD365; T-Cell Immunoglobulin Mucin Family Member 1; T-Cell Immunoglobulin Mucin Receptor 1; T-Cell Membrane Protein 1; TIMD-1; KIM-1; TIM; T-Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T Cell Immunoglobin Domain And Mucin Domain Protein 1; CD365 Antigen; HAVcr |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS containing 0.02% sodium azide |
| Preservative | 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5QNS5 Mouse Hepatitis A virus cellular receptor 1 homolog Swiss-port # Q96D42 Human Hepatitis A virus cellular receptor 1 |
|---|---|
| Gene Symbol | HAVCR1 |
| Gene Full Name | Hepatitis A Virus Cellular Receptor 1 |
| Background | The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. The protein is a receptor for multiple other viruses, including Ebola virus, Marburg virus, Dengue virus, and Zika virus and is a possible entry factor for SARS-CoV-2 and other coronaviruses. |
| Function | Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions. |
| Cellular Localization | Cell membrane, Membrane |
| Calculated MW | 39 kDa |
| PTM | Disulfide bond, Glycoprotein, Isopeptide bond, Ubl conjugation |
Images (2) Click the Picture to Zoom In
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ARG44017 anti-TIM1 / KIM1 antibody IHC-P image
Immunohistochemistry: Human uterus stained with ARG44017 anti-TIM1 / KIM1 antibody at 10 μg/mL dilution.
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ARG44017 anti-TIM1 / KIM1 antibody WB image
Western blot: 293T, A431 and A549 stained with ARG44017 anti-TIM1 / KIM1 antibody at 8 μg/ml dilution.
