ARG43742
anti-TMEM176B / LR8 antibody
anti-TMEM176B / LR8 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TMEM176B / LR8 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Cow, Dog, Hrs, Pig |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMEM176B / LR8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the C-terminal region of Human TMEM176B / LR8. (within the following region: SLVSL GVGLR NLCGQ SSQPL NEEGS EKRLL GENSV PPSPS REQTS TAIVL) |
| Conjugation | Un-conjugated |
| Protein Full Name | Transmembrane protein 176B |
| Alternate Names | LR8; MS4B2; Transmembrane protein 176B; TMEM176B |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based On Immunogen Sequence: Cow: 85%; Dog: 85%; Horse: 85%; Pig: 85%; | ||||
|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | OVCAR-3 | ||||
| Observed Size | ~ 32 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TMEM176B |
| Gene Full Name | transmembrane protein 176B |
| Background | Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be located in nuclear membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity). [UniProt] |
| Cellular Localization | Membrane, Nucleus. [UniProt] |
| Calculated MW | 25.3, 29 kDa |
| PTM | Phosphoprotein |
Images (1) Click the Picture to Zoom In
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ARG43742 anti-TMEM176B / LR8 antibody WB image
Western blot: OVCAR-3 cell lysate stained with ARG43742 anti-TMEM176B / LR8 antibody.
