ARG44530
anti-TNRC6C antibody
anti-TNRC6C antibody for Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TNRC6C |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TNRC6C |
| Antigen Species | Human |
| Immunogen | Human TNRC6C recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | TNRC6C; Trinucleotide Repeat Containing Adaptor 6C; KIAA1582 Trinucleotide Repeat-Containing Gene 6C Protein; Trinucleotide Repeat Containing 6C; FLJ20015 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9HCJ0 Human Trinucleotide repeat-containing gene 6C protein |
|---|---|
| Gene Symbol | TNRC6C |
| Gene Full Name | Trinucleotide Repeat Containing Adaptor 6C |
| Background | Predicted to enable RNA binding activity. Involved in gene silencing by miRNA; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. |
| Function | Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. |
| Calculated MW | 201 kDa |
| PTM | Methylation, Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG44530 anti-TNRC6C antibody WB image
Western blot: Jurkat, SH-SY5Y and HEL stained with ARG44530 anti-TNRC6C antibody at 0.5 μg/mL dilution.
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ARG44530 anti-TNRC6C antibody FACS image
Flow Cytometry: U251 stained with ARG44530 anti-TNRC6C antibody at 1 μg/10^6 cells dilution.
