ARG45256
anti-TPP2 antibody
anti-TPP2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes TPP2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TPP2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human TPP2. |
| Conjugation | Un-conjugated |
| Alternate Names | Tripeptidyl peptidase II; TPP2; Tripeptidyl Peptidase 2; TPPII; Tripeptidyl Aminopeptidase; Tripeptidyl-Peptidase II; Tripeptidyl-Peptidase 2; EC 3.4.14.10; TPP-II; TPP-2; Tripeptidyl Peptidase II; IMD78; TPPII |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 138 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TPP2 |
| Gene Full Name | Tripeptidyl Peptidase 2 |
| Background | Tripeptidyl-peptidase 2 is an enzyme that in humans is encoded by the TPP2 gene. This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.. [provided by RefSeq, Jul 2008] |
| Function | Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. [UniProt] |
| Cellular Localization | Nucleus; Cytoplasm. [UniProt] |
| Calculated MW | 105 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
