ARG44595
anti-TREM1 antibody [6B1] (APC)
anti-TREM1 antibody [6B1] (APC) for Flow cytometry and Human
Overview
| Product Description | APC-conjugated Mouse Monoclonal antibody recognizes TREM1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 6B1 |
| Isotype | IgG1 |
| Target Name | TREM1 |
| Antigen Species | Human |
| Conjugation | APC |
| Alternate Names | TREM1; Triggering Receptor Expressed On Myeloid Cells 1; TREM-1; CD354; Triggering Receptor Expressed On Monocytes 1; CD354 Antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NP99 Human Triggering receptor expressed on myeloid cells 1 |
|---|---|
| Gene Symbol | TREM1 |
| Gene Full Name | Triggering Receptor Expressed On Myeloid Cells 1 |
| Background | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
| Function | By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis. [UniProt] |
| Cellular Localization | Cell membrane, Membrane, Secreted. [UniProt] |
| Calculated MW | 26 kDa |
| PTM | Disulfide bond, Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG44595 anti-TREM1 antibody [6B1] (APC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG44595 anti-TREM1 antibody [6B1] (APC) at 10 μl/ 100 μl dilution.
