ARG43857
anti-TREM1 antibody [6B1]
anti-TREM1 antibody [6B1] for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes TREM1. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 6B1 |
| Isotype | IgG1 |
| Target Name | TREM1 |
| Antigen Species | Human |
| Immunogen | Human TREM1 recombinant protein. |
| Conjugation | Un-conjugated |
| Protein Full Name | Triggering receptor expressed on myeloid cells 1 |
| Alternate Names | TREM1; Triggering Receptor Expressed On Myeloid Cells 1; TREM-1; CD354; Triggering Receptor Expressed On Monocytes 1; CD354 Antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein-A affinity chromatography |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 4°C. Keep protected from prolonged exposure to light. Do not freeze. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # Q9NP99 Human Triggering receptor expressed on myeloid cells 1 |
|---|---|
| Gene Symbol | TREM1 |
| Gene Full Name | Triggering Receptor Expressed On Myeloid Cells 1 |
| Background | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Function | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. [UniProt] |
| Cellular Localization | Cell membrane, Membrane, Secreted |
| Calculated MW | 26 kDa |
| PTM | Disulfide bond; Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG43857 anti-TREM1 antibody [6B1] FACS image
Flow Cytometry: Human whole blood stained with ARG43857 anti-TREM1 antibody [6B1] at 1.67 μg/ml.
