ARG57182
anti-TRIM58 antibody
anti-TRIM58 antibody for Western blot and Human,Mouse
1
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TRIM58 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRIM58 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 457-486 (C-terminus) of Human TRIM58. |
| Conjugation | Un-conjugated |
| Alternate Names | Tripartite motif-containing protein 58; Protein BIA2; BIA2; E3 ubiquitin-protein ligase TRIM58; EC 6.3.2.- |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | CEM |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5NCC9 Mouse E3 ubiquitin-protein ligase TRIM58 Swiss-port # Q8NG06 Human E3 ubiquitin-protein ligase TRIM58 |
|---|---|
| Gene Symbol | TRIM58 |
| Gene Full Name | tripartite motif containing 58 |
| Function | E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization. [UniProt] |
| Calculated MW | 55 kDa |
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