ARG45328
anti-TRMT6 antibody
anti-TRMT6 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Polyclonal antibody recognizes TRMT6 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRMT6 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human TRMT6. |
| Conjugation | Un-conjugated |
| Alternate Names | TRMT6; TRNA Methyltransferase 6 Non-Catalytic Subunit; Gcd10p; CGI-09; GCD10; MRNA Methyladenosine-N(1)-Methyltransferase Non-Catalytic Subunit TRM6; TRNA (Adenine(58)-N(1))-Methyltransferase Non-Catalytic Subunit TRM6; TRNA(M1A58)MTase Subunit TRM6; MGC5029; TRM6; TRNA Methyltransferase 6 Homolog (S. Cerevisiae); TRNA(M1A58)-Methyltransferase Subunit TRM6; TRNA Methyltransferase 6 Homolog; TRNA Methyltransferase 6; KIAA1153 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 60 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9UJA5 Human tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
|---|---|
| Gene Symbol | TRMT6 |
| Gene Full Name | TRNA Methyltransferase 6 Non-Catalytic Subunit |
| Background | This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Function | Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 56 kDa |
| PTM | Phosphoprotein. [UniProt] |
