ARG45656
anti-TRNT1 antibody
anti-TRNT1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TRNT1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRNT1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human TRNT1. |
| Conjugation | Un-conjugated |
| Alternate Names | TRNT1; TRNA Nucleotidyl Transferase 1; CGI-47; MtCCA; CCA1; CCA TRNA Nucleotidyltransferase 1, Mitochondrial; TRNA Nucleotidyl Transferase, CCA-Adding, 1; ATP(CTP):TRNA Nucleotidyltransferase; TRNA CCA Nucleotidyl Transferase 1; Mt TRNA CCA-Pyrophosphorylase; Mt TRNA CCA-Diphosphorylase; Mt TRNA Adenylyltransferase; Mt CCA-Adding Enzyme; CCA-Adding Enzyme; Mitochondrial TRNA Nucleotidyl Transferase, CCA-Adding; Mitochondrial CCA-Adding TRNA-Nucleotidyltransferase; TRNA-Nucleotidyltransferase 1, Mitochondrial; EC 2.7.7.72; RPEM; SIFD |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96Q11 Human CCA tRNA nucleotidyltransferase 1, mitochondrial |
|---|---|
| Gene Symbol | TRNT1 |
| Gene Full Name | TRNA Nucleotidyl Transferase 1 |
| Background | The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Function | Nucleotidyltransferase that catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs, which is necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates. [UniProt] |
| Cellular Localization | Cytoplasm; Mitochondrion; Nucleus. [UniProt] |
| Calculated MW | 50 kDa |
| PTM | Acetylation; Disulfide bond; Phosphoprotein. [UniProt] |
