ARG67244
anti-TRPV4 antibody
anti-TRPV4 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TRPV4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRPV4 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TRPV4. |
| Conjugation | Un-conjugated |
| Alternate Names | TRPV4; Transient Receptor Potential Cation Channel Subfamily V Member 4; OTRPC4; TRP12; VROAC; VR-OAC; VRL-2; CMT2C; Osmosensitive Transient Receptor Potential Channel 4; Transient Receptor Potential Protein 12; Vanilloid Receptor-Like Channel 2; Osm-9-Like TRP Channel 4; VRL2; Transient Receptor Potential Cation Channel, Subfamily V, Member 4; Vanilloid Receptor-Related Osmotically Activated Channel; Vanilloid Receptor-Related Osmotically-Activated Channel; OSM9-Like Transient Receptor Potential Channel 4; Vanilloid Receptor-Like Protein 2; HMSN2C; SSQTL1; BCYM3; SPSMA; TrpV4; SMAL |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 30% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TRPV4 |
| Gene Full Name | Transient Receptor Potential Cation Channel Subfamily V Member 4 |
| Background | This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
| Function | In neurons of the central nervous system, could play a role in triggering voluntary water intake in response to increased sodium concentration in body fluid. [Uniprot] |
| Cellular Localization | Cell junction, Cell membrane, Cell projection, Cilium, Endoplasmic reticulum, Membrane. [Uniprot] |
| Calculated MW | 98 kDa |
| PTM | Phosphoprotein. [Uniprot] |
