ARG44071
anti-TSC22D1 antibody
anti-TSC22D1 antibody for Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal recognizes TSC22D1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TSC22D1 |
| Antigen Species | Human |
| Immunogen | Human TSC22D1 recombinant protein (Position: N179-Q926). |
| Conjugation | Un-conjugated |
| Alternate Names | TSC22D1; TSC22 Domain Family Member 1; TSC22; TGFB1I4; Transforming Growth Factor Beta-1-Induced Transcript 4 Protein; TGFB-Stimulated Clone 22 Homolog; TSC22 Domain Family Protein 1; Regulatory Protein TSC-22; Cerebral Protein 2; MGC17597; Transforming Growth Factor Beta-Stimulated Protein TSC-22; Transforming Growth Factor Beta 1 Induced Transcript 4; Transcriptional Regulator TSC-22; TSC22 Domain Family, Member 1; TGFbeta-Stimulated Clone 22; KIAA1994; Ptg-2 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TSC22D1 |
| Gene Full Name | TSC22 Domain Family Member 1 |
| Background | This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Function | Contributes to enhancement of TGF-beta signaling by binding to and modulating the transcription activator activity of SMAD4. |
| Cellular Localization | Cell membrane, Cytoplasm, Membrane, Mitochondrion, Nucleus |
| Calculated MW | 110 kDa |
| PTM | Phosphoprotein |
Images (4) Click the Picture to Zoom In
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ARG44071 anti-TSC22D1 antibody WB image
Western blot: A549, 293T and MCF-7 stained with ARG44071 anti-TSC22D1 antibody at 0.5 μg/mL dilution.
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ARG44071 anti-TSC22D1 antibody FACS image
Flow Cytometry: SH-SY5Y stained with ARG44071 anti-TSC22D1 antibody at 1 μg/1x10^6 cells dilution.
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ARG44071 anti-TSC22D1 antibody WB image
Western blot: Rat brain and C6 stained with ARG44071 anti-TSC22D1 antibody at 0.5 μg/mL dilution.
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ARG44071 anti-TSC22D1 antibody WB image
Western blot: Mouse brain and NIH/3T3 stained with ARG44071 anti-TSC22D1 antibody at 0.5 μg/mL dilution.
