ARG57169
anti-TXN2 / Thioredoxin 2 antibody [1B1]
anti-TXN2 / Thioredoxin 2 antibody [1B1] for ICC/IF,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1B1] recognizes TXN2 / Thioredoxin 2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1B1 |
| Isotype | IgG2b, kappa |
| Target Name | TXN2 / Thioredoxin 2 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 60-166 of Human TXN2 / Thioredoxin-2 |
| Conjugation | Un-conjugated |
| Alternate Names | TRX2; MT-TRX; Mt-Trx; Thioredoxin-2; Thioredoxin, mitochondrial; MTRX |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TXN2 |
| Gene Full Name | thioredoxin 2 |
| Background | This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008] |
| Function | Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. [UniProt] |
| Calculated MW | 18 kDa |
Images (3) Click the Picture to Zoom In
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ARG57169 anti-TXN2 / Thioredoxin 2 antibody [1B1] ICC/IF image
Immunofluorescence: HeLa cells line stained with ARG57169 anti-TXN2 / Thioredoxin 2 antibody [1B1] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
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ARG57169 anti-TXN2 / Thioredoxin 2 antibody [1B1] WB image
Western blot: 40 µg of 1) HepG2, 2) HeLa, 3) Raji, 4) K562, 5) Jurkat, 6) A431, 7) MCF7, and 8) THP1 cell lysates stained with ARG57169 anti-TXN2 / Thioredoxin 2 antibody [1B1] at 1:1000.
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ARG57169 anti-TXN2 / Thioredoxin 2 antibody [1B1] WB image
Western blot: 50 ng of 1) Recombinant Human Thioredoxin1 protein, and 2) Recombinant Human Thioredoxin2 protein stained with ARG57169 anti-TXN2 / Thioredoxin 2 antibody [1B1] at 1:1000.
