Overview

Product Description	Rabbit Polyclonal antibody recognizes VGluT1
Tested Reactivity	Hu, Ms, Rat
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	VGluT1
Antigen Species	Human
Immunogen	Synthetic peptide derived from Human VGluT1.
Conjugation	Un-conjugated
Alternate Names	Brain-specific Na; Vesicular glutamate transporter 1; Solute carrier family 17 member 7; VGLUT1; BNPI; VGluT1

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 116638 Rat SLC17A7 GeneID: 57030 Human SLC17A7 GeneID: 72961 Mouse SLC17A7 Swiss-port # Q3TXX4 Mouse Vesicular glutamate transporter 1 Swiss-port # Q62634 Rat Vesicular glutamate transporter 1 Swiss-port # Q9P2U7 Human Vesicular glutamate transporter 1 More
Gene Symbol	SLC17A7
Gene Full Name	solute carrier family 17 (vesicular glutamate transporter), member 7
Background	The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]
Function	Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. [UniProt]
Cellular Localization	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. [UniProt]
Calculated MW	62 kDa

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